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DIAPH3 Antibody (internal region, near the C-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NSV4
Other Accession NP_001035982.1, NP_112194.2, 81624
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 136926 Da
Additional Information
Gene ID 81624
Other Names Protein diaphanous homolog 3, Diaphanous-related formin-3, DRF3, MDia2, DIAPH3, DIAP3
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDIAPH3 Antibody (internal region, near the C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms DIAP3
Function Binds to GTP-bound form of Rho and to profilin. Acts in a Rho-dependent manner to recruit profilin to the membrane, where it promotes actin polymerization. It is required for cytokinesis, stress fiber formation, and transcriptional activation of the serum response factor. DFR proteins couple Rho and Src tyrosine kinase during signaling and the regulation of actin dynamics (By similarity).
Cellular Location Cytoplasm, cytosol Note=During mitosis, co-localizes with the actin-rich cleavage furrow and with the microtubule-rich central spindle during cytokinesis
Research Areas
Citations (0)

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This antibody is expected to recognise both reported isoforms (NP_001035982.1 and NP_112194.2).


Novel roles of formin mDia2 in lamellipodia and filopodia formation in motile
cells. Yang C, Czech L, Gerboth S, Kojima S, Scita G, Svitkina T. PLoS Biol. 2007 Nov;5(11):e317. PMID: 18044991

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$ 325.00
Cat# AF2653a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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