|Other Accession||NP_002933.1, 6092, 268902 (mouse), 84409 (rat)|
|Predicted||Human, Mouse, Rat, Dog|
|Calculated MW||151200 Da|
|Other Names||Roundabout homolog 2, ROBO2, KIAA1568|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ROBO2 Antibody (internal region, near the C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for SLIT2, and probably SLIT1, which are thought to act as molecular guidance cue in cellular migration, including axonal navigation at the ventral midline of the neural tube and projection of axons to different regions during neuronal development.|
|Cellular Location||Membrane; Single-pass type I membrane protein|
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Provided below are standard protocols that you may find useful for product applications.
The slit receptor EVA-1 coactivates a SAX-3/Robo mediated guidance signal in C. elegans. Fujisawa K, Wrana JL, Culotti JG. Science. 2007 Sep 28;317(5846):1934-8. PMID: 17901337
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