|Other Accession||NP_006696.1, 10912, 23882 (mouse), 291005 (rat)|
|Predicted||Human, Mouse, Rat|
|Calculated MW||17121 Da|
|Other Names||Growth arrest and DNA damage-inducible protein GADD45 gamma, Cytokine-responsive protein CR6, DNA damage-inducible transcript 2 protein, DDIT-2, GADD45G, CR6, DDIT2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GADD45gamma (aa 18 to 28) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Involved in the regulation of growth and apoptosis. Mediates activation of stress-responsive MTK1/MEKK4 MAPKKK.|
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Provided below are standard protocols that you may find useful for product applications.
NF-kappa B-mediated repression of growth arrest- and DNA-damage-inducible
proteins 45alpha and gamma is essential for cancer cell survival. Zerbini LF, Wang Y, Czibere A, Correa RG, Cho JY, Ijiri K, Wei W, Joseph M, Gu X, Grall F, Goldring MB, Zhou JR, Libermann TA. Proc Natl Acad Sci U S A. 2004 Sep 14;101(37):13618-23. PMID: 15353598
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