- CITATIONS: 1
|Other Accession||NP_005977.2, 6656|
|Calculated MW||39023 Da|
|Other Names||Transcription factor SOX-1, SOX1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SOX1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Transcriptional activator. May function as a switch in neuronal development. Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity).|
|Tissue Location||Mainly expressed in the developing central nervous system|
Provided below are standard protocols that you may find useful for product applications.
Sox1 acts through multiple independent pathways to promote neurogenesis. Kan L, Israsena N, Zhang Z, Hu M, Zhao LR, Jalali A, Sahni V, Kessler JA. Dev Biol. 2004 May 15;269(2):580-94. PMID: 15110721
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