HRASLS / H-REV107 (internal) Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
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Primary Accession | Q9HDD0 |
Other Accession | NP_065119.1, 57110, 27281 (mouse), 288025 (rat) |
Predicted | Human, Mouse, Rat |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 18750 Da |
Gene ID | 57110 |
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Other Names | Phospholipid-metabolizing enzyme A-C1, 2.3.1.-, 3.1.1.-, HRAS-like suppressor 1, HRSL1, HRASLS |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | HRASLS / H-REV107 (internal) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | PLAAT1 (HGNC:14922) |
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Synonyms | HRASLS |
Function | Exhibits both phospholipase A1/2 and acyltransferase activities (PubMed:21880860, PubMed:26503625). Shows phospholipase A1 (PLA1) and A2 (PLA2) activity, catalyzing the calcium-independent release of fatty acids from the sn-1 or sn-2 position of glycerophospholipids (PubMed:21880860, PubMed:22825852, PubMed:27623847). Shows O-acyltransferase activity, catalyzing the transfer of a fatty acyl group from glycerophospholipid to the hydroxyl group of lysophospholipid (PubMed:21880860). Shows N-acyltransferase activity, catalyzing the calcium-independent transfer of a fatty acyl group at the sn-1 position of phosphatidylcholine (PC) and other glycerophospholipids to the primary amine of phosphatidylethanolamine (PE), forming N-acylphosphatidylethanolamine (NAPE) which serves as precursor for N-acylethanolamines (NAEs) (PubMed:21880860, PubMed:22825852, PubMed:27623847). |
Cellular Location | [Isoform 1]: Membrane; Single-pass membrane protein. Cytoplasm |
Tissue Location | [Isoform 1]: Abundantly expressed in testis, skeletal muscle, brain, and heart. |
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Provided below are standard protocols that you may find useful for product applications.
References
Promoter hypermethylation of CCNA1, RARRES1, and HRASLS3 in nasopharyngeal carcinoma. Yanatatsaneejit P, Chalermchai T, Kerekhanjanarong V, Shotelersuk K, Supiyaphun P, Mutirangura A, Sriuranpong V. Oral Oncol. 2007 Aug 2 PMID: 17689134
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