|Other Accession||NP_064524.3, 56898, 69772 (mouse), 295458 (rat)|
|Predicted||Human, Mouse, Rat, Cow|
|Calculated MW||26724 Da|
|Other Names||3-hydroxybutyrate dehydrogenase type 2, 1.1.1.-, 18.104.22.168, Dehydrogenase/reductase SDR family member 6, Oxidoreductase UCPA, R-beta-hydroxybutyrate dehydrogenase, Short chain dehydrogenase/reductase family 15C member 1, BDH2, DHRS6, SDR15C1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||BDH2 / DHRS6 (aa 92 to 103) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Dehydrogenase that mediates the formation of 2,5- dihydroxybenzoic acid (2,5-DHBA), a siderophore that shares structural similarities with bacterial enterobactin and associates with LCN2, thereby playing a key role in iron homeostasis and transport. Also acts as a 3-hydroxybutyrate dehydrogenase (By similarity).|
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Provided below are standard protocols that you may find useful for product applications.
Characterization of human DHRS6, an orphan short chain dehydrogenase/reductase enzyme: a novel, cytosolic type 2 R-beta-hydroxybutyrate dehydrogenase. Guo K, Lukacik P, Papagrigoriou E, Meier M, Lee WH, Adamski J, Oppermann U. J Biol Chem. 2006 Apr 14;281(15):10291-7. Epub 2005 Dec 27. PMID: 16380372
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