|Other Accession||NP_001048.2, 6865|
|Calculated MW||44442 Da|
|Other Names||Substance-K receptor, SKR, NK-2 receptor, NK-2R, Neurokinin A receptor, Tachykinin receptor 2, TACR2, NK2R, NKNAR, TAC2R|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TACR2 / Neurokinin 2 receptor Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||NK2R, NKNAR, TAC2R|
|Function||This is a receptor for the tachykinin neuropeptide substance K (neurokinin A). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: substance K > neuromedin-K > substance P.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Increased neurokinin-2 receptor expression in alveolar macrophages of smokers with COPD. Miotto D, Boschetto P, Cavallesco G, Zeni E, Querzoli P, Pedriali M, Chiarelli S, Fabbri LM, Mapp CE. Histopathology. 2007 Jul;51(1):128-31. Epub 2007 May 26. No abstract available. PMID: 17532769
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