|Application ||WB, E|
|Other Accession||NP_005904.1, 4161, 17203 (mouse)|
|Calculated MW||36601 Da|
|Other Names||Melanocortin receptor 5, MC5-R, MC-2, MC5R|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MC5R Antibody (N-Term, near) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Receptor for MSH (alpha, beta and gamma) and ACTH. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. This receptor is a possible mediator of the immunomodulation properties of melanocortins.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in the brain but not in the melanoma cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Further structure-activity studies of lactam derivatives of MT-II and SHU-9119: their activity and selectivity at human melanocortin receptors 3, 4, and 5. Grieco P, Cai M, Han G, Trivedi D, Campiglia P, Novellino E, Hruby VJ. Peptides. 2007 Jun;28(6):1191-6. Epub 2007 Mar 1. PMID: 17482720
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