|Other Accession||NP_009206.1, 11334, 80385 (mouse), 501052 (rat)|
|Predicted||Human, Mouse, Rat|
|Calculated MW||12074 Da|
|Other Names||Tumor suppressor candidate 2, Fusion 1 protein, Fus-1 protein, PDGFA-associated protein 2, TUSC2, C3orf11, FUS1, LGCC, PDAP2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TUSC2 / FUS1 Antibody (interal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||C3orf11, FUS1, LGCC, PDAP2|
|Function||May function as a tumor suppressor, inhibiting colony formation, causing G1 arrest and ultimately inducing apoptosis in homozygous 3p21.3 120-kb region-deficient cells.|
|Tissue Location||Strong expression in heart, lung, skeletal muscle, kidney, and pancreas, followed by brain and liver, lowest levels in placenta|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Synergistic tumor suppression by coexpression of FUS1 and p53 is associated with down-regulation of murine double minute-2 and activation of the apoptotic protease-activating factor 1-dependent apoptotic pathway in human non-small cell lung cancer cells Deng WG, Kawashima H, Wu G, Jayachandran G, Xu K, Minna JD, Roth JA, Ji L. Cancer Res. 2007 Jan 15;67(2):709-17. PMID: 17234782
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