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CHRNB4 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| E |
|---|---|
| Primary Accession | P30926 |
| Other Accession | NP_000741.1, 1143 |
| Predicted | Human, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 56380 Da |
| Gene ID | 1143 |
|---|---|
| Other Names | Neuronal acetylcholine receptor subunit beta-4, CHRNB4 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | CHRNB4 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | CHRNB4 |
|---|---|
| Function | After binding acetylcholine, the AChR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane. |
| Cellular Location | Postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
The immunizing peptide represents part of the first exrracellular domain (aa22-236).
References
Functional polymorphisms in the human beta4 subunit of nicotinic acetylcholine receptors. Liang Y, Salas R, Marubio L, Bercovich D, De Biasi M, Beaudet AL, Dani JA. Neurogenetics. 2005 Feb;6(1):37-44. Epub 2004 Nov 25. PMID: 15742216
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