|Other Accession||NP_056465.2, 26146|
|Calculated MW||78632 Da|
|Other Names||TRAF3-interacting protein 1, Interleukin-13 receptor alpha 1-binding protein 1, Intraflagellar transport protein 54 homolog, Microtubule-interacting protein associated with TRAF3, MIP-T3, TRAF3IP1, IFT54, MIPT3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRAF3IP1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules.|
|Cellular Location||Cytoplasm, cytoskeleton. Cell projection, cilium. Note=Microtubules|
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Provided below are standard protocols that you may find useful for product applications.
MIP-T3 associates with IL-13Ralpha1 and suppresses STAT6 activation in response to IL-13 stimulation. Niu Y, Murata T, Watanabe K, Kawakami K, Yoshimura A, Inoue J, Puri RK, Kobayashi N. FEBS Lett. 2003 Aug 28;550(1-3):139-43. PMID: 12935900
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