|Other Accession||NP_536723.2, 89778|
|Calculated MW||44099 Da|
|Other Names||Serpin B11, SERPINB11|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SERPINB11 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Has no serine protease inhibitory activity, probably due to mutations in the scaffold impairing conformational change.|
|Tissue Location||Detected in a restricted number of tissues, including lung, placenta, prostate, and tonsil|
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Provided below are standard protocols that you may find useful for product applications.
SERPINB11 is a new noninhibitory intracellular serpin. Common single nucleotide polymorphisms in the scaffold impair conformational change. Askew DJ, Cataltepe S, Kumar V, Edwards C, Pace SM, Howarth RN, Pak SC, Askew YS, Brömme D, Luke CJ, Whisstock JC, Silverman GA. J Biol Chem. 2007 Aug 24;282(34):24948-60. Epub 2007 Jun 11. PMID: 17562709
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