|Application ||WB, E|
|Other Accession||NP_000033.2, 350|
|Calculated MW||38298 Da|
|Other Names||Beta-2-glycoprotein 1, APC inhibitor, Activated protein C-binding protein, Anticardiolipin cofactor, Apolipoprotein H, Apo-H, Beta-2-glycoprotein I, B2GPI, Beta(2)GPI, APOH, B2G1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Apolipoprotein H Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.|
|Tissue Location||Expressed by the liver and secreted in plasma.|
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Provided below are standard protocols that you may find useful for product applications.
Plasmin-cleaved beta-2-glycoprotein 1 is an inhibitor of angiogenesis Sakai T, Balasubramanian K, Maiti S, Halder JB, Schroit AJ Am J Pathol. 2007 Nov;171(5):1659-69 PMID: 17872974
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