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BMPR2 Antibody (internal)

Peptide-affinity purified goat antibody

  • WB - BMPR2 Antibody (internal) AF2818a
    AF2818a (1 µg/ml) staining of Human Liver lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13873
Other Accession NP_001195.2, 659
Reactivity Human
Predicted Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 115201 Da
Additional Information
Gene ID 659
Other Names Bone morphogenetic protein receptor type-2, BMP type-2 receptor, BMPR-2,, Bone morphogenetic protein receptor type II, BMP type II receptor, BMPR-II, BMPR2, PPH1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsBMPR2 Antibody (internal) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name BMPR2
Synonyms PPH1
Function On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Binds to BMP-7, BMP-2 and, less efficiently, BMP-4. Binding is weak but enhanced by the presence of type I receptors for BMPs.
Cellular Location Cell membrane; Single-pass type I membrane protein
Tissue Location Highly expressed in heart and liver.
Research Areas
Citations (0)

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Stromal inactivation of BMPRII leads to colorectal epithelial overgrowth and polyp formation Beppu H, Mwizerwa ON, Beppu Y, Dattwyler MP, Lauwers GY, Bloch KD, Goldstein AM Oncogene. 2008 Feb 14;27(8):1063-70. Epub 2007 Aug 13 PMID: 17700526

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$ 325.00
Cat# AF2818a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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