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> home > Products > Primary Antibodies > Antibody Collections > Goat Antibodies > ODZ3 / Teneurin-3 Antibody (internal region)
ODZ3 / Teneurin-3 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
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- BACKGROUND
Application 
| IHC, IF, E |
|---|---|
| Primary Accession | Q9P273 |
| Other Accession | NP_001073946.1, 55714, 23965 (mouse) |
| Reactivity | Human |
| Predicted | Mouse, Rat, Pig, Dog, Cow |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 300950 Da |
| Gene ID | 55714 |
|---|---|
| Other Names | Teneurin-3, Ten-3, Protein Odd Oz/ten-m homolog 3, Tenascin-M3, Ten-m3, Teneurin transmembrane protein 3, TENM3, KIAA1455, ODZ3, TNM3 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | ODZ3 / Teneurin-3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TENM3 (HGNC:29944) |
|---|---|
| Function | Involved in neural development by regulating the establishment of proper connectivity within the nervous system. Acts in both pre- and postsynaptic neurons in the hippocampus to control the assembly of a precise topographic projection: required in both CA1 and subicular neurons for the precise targeting of proximal CA1 axons to distal subiculum, probably by promoting homophilic cell adhesion. Required for proper dendrite morphogenesis and axon targeting in the vertebrate visual system, thereby playing a key role in the development of the visual pathway. Regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May also be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes. |
| Cellular Location | Cell membrane {ECO:0000250|UniProtKB:Q9WTS6}; Single-pass membrane protein {ECO:0000250|UniProtKB:Q9WTS6}. Cell projection, axon {ECO:0000250|UniProtKB:Q9WTS6} |
| Tissue Location | Expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver Expression was high in brain, with highest levels in amygdala and caudate nucleus, followed by thalamus and subthalamic nucleus |
Research Areas
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Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with
expression implying distinct yet overlapping developmental roles. Ben-Zur T, Feige E, Motro B, Wides R. Dev Biol. 2000 Jan 1;217(1):107-20. PMID: 10625539
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$ 341.00
Cat# AF2827a
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