|Application ||IHC, IF, E|
|Other Accession||NP_001073946.1, 55714, 23965 (mouse)|
|Predicted||Mouse, Rat, Pig, Dog, Cow|
|Calculated MW||300950 Da|
|Other Names||Teneurin-3, Ten-3, Protein Odd Oz/ten-m homolog 3, Tenascin-M3, Ten-m3, Teneurin transmembrane protein 3, TENM3, KIAA1455, ODZ3, TNM3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||ODZ3 / Teneurin-3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||KIAA1455, ODZ3, TNM3|
|Function||Involved in neural development, regulating the establishment of proper connectivity within the nervous system. Promotes axon guidance and homophilic cell adhesion. Plays a role in the development of the visual pathway; regulates the formation in ipsilateral retinal mapping to both the dorsal lateral geniculate nucleus (dLGN) and the superior colliculus (SC). May be involved in the differentiation of the fibroblast-like cells in the superficial layer of mandibular condylar cartilage into chondrocytes. May function as a cellular signal transducer (By similarity).|
|Cellular Location||Membrane; Single-pass membrane protein. Cell projection, axon|
|Tissue Location||Expressed in adult and fetal brain, slightly lower levels in testis and ovary, and intermediate levels in all other peripheral tissues examined. Not expressed in spleen or liver. Expression was high in brain, with highest levels in amygdala and caudate nucleus, followed by thalamus and subthalamic nucleus.|
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Provided below are standard protocols that you may find useful for product applications.
The mammalian Odz gene family: homologs of a Drosophila pair-rule gene with
expression implying distinct yet overlapping developmental roles. Ben-Zur T, Feige E, Motro B, Wides R. Dev Biol. 2000 Jan 1;217(1):107-20. PMID: 10625539
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