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RPS6KA2 Antibody (C-Term, near)

Peptide-affinity purified goat antibody

  • WB - RPS6KA2 Antibody (C-Term, near) AF2830a
    AF2830a (1 µg/ml) staining of Rat Lung lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • WB - RPS6KA2 Antibody (C-Term, near) AF2830a
    AF2830a (0.01 µg/ml) staining of Mouse Lung lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q15349
Other Accession NP_066958.2, NP_001006933.1, 6196
Reactivity Rat
Predicted Human, Mouse, Horse
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 83239 Da
Additional Information
Gene ID 6196
Other Names Ribosomal protein S6 kinase alpha-2, S6K-alpha-2,, 90 kDa ribosomal protein S6 kinase 2, p90-RSK 2, p90RSK2, MAP kinase-activated protein kinase 1c, MAPK-activated protein kinase 1c, MAPKAP kinase 1c, MAPKAPK-1c, Ribosomal S6 kinase 3, RSK-3, pp90RSK3, RPS6KA2, MAPKAPK1C, RSK3
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsRPS6KA2 Antibody (C-Term, near) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name RPS6KA2
Synonyms MAPKAPK1C, RSK3
Function Serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. May function as tumor suppressor in epithelial ovarian cancer cells.
Cellular Location Nucleus. Cytoplasm
Tissue Location Widely expressed with higher expression in lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_066958.2; NP_001006933.1)


FGFR3 activates RSK2 to mediate hematopoietic transformation through tyrosine phosphorylation of RSK2 and activation of the MEK/ERK pathway Kang S, Dong S, Gu TL, Guo A, Cohen MS, Lonial S, Khoury HJ, Fabbro D, Gilliland DG, Bergsagel PL, Taunton J, Polakiewicz RD, Chen J Cancer Cell. 2007 Sep;12(3):201-14 PMID: 17785202

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$ 325.00
Cat# AF2830a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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