|Other Accession||NP_689414.1, 83756|
|Calculated MW||93386 Da|
|Other Names||Taste receptor type 1 member 3, Sweet taste receptor T1R3, TAS1R3, T1R3, TR3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||T1R3 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Putative taste receptor. TAS1R1/TAS1R3 responds to the umami taste stimulus (the taste of monosodium glutamate). TAS1R2/TAS1R3 recognizes diverse natural and synthetic sweeteners. TAS1R3 is essential for the recognition and response to the disaccharide trehalose (By similarity). Sequence differences within and between species can significantly influence the selectivity and specificity of taste responses.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
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Provided below are standard protocols that you may find useful for product applications.
Detection of sweet and umami taste in the absence of taste receptor T1r3. Damak S, Rong M, Yasumatsu K, Kokrashvili Z, Varadarajan V, Zou S, Jiang P, Ninomiya Y, Margolskee RF. Science. 2003 Aug 8;301(5634):850-3. PMID: 12869700
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