|Other Accession||NP_003854.1, 8818|
|Calculated MW||9312 Da|
|Other Names||Dolichol phosphate-mannose biosynthesis regulatory protein, Dolichol-phosphate mannose synthase subunit 2, DPM synthase subunit 2, DPM2|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DPM2 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Regulates the biosynthesis of dolichol phosphate- mannose. Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization and stable expression of DPM1. When associated with the GPI-GlcNAc transferase (GPI-GnT) complex enhances but is not essential for its activity.|
|Cellular Location||Endoplasmic reticulum membrane; Multi-pass membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Initial enzyme for glycosylphosphatidylinositol biosynthesis requires PIG-P and is regulated by DPM2. Watanabe R, Murakami Y, Marmor MD, Inoue N, Maeda Y, Hino J, Kangawa K, Julius M, Kinoshita T. EMBO J. 2000 Aug 15;19(16):4402-11. PMID: 10944123
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