|Other Accession||NP_060237.2, NP_570901.2, 55630|
|Calculated MW||68392 Da|
|Other Names||Zinc transporter ZIP4, Solute carrier family 39 member 4, Zrt- and Irt-like protein 4, ZIP-4, SLC39A4, ZIP4|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SLC39A4 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Plays an important role in cellular zinc homeostasis as a zinc transporter. Regulated in response to zinc availability (By similarity).|
|Cellular Location||Cell membrane; Multi-pass membrane protein Recycling endosome membrane; Multi- pass membrane protein Note=Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability|
|Tissue Location||Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_060237.2; NP_570901.2)
Aberrant expression of zinc transporter ZIP4 (SLC39A4) significantly contributes to human pancreatic cancer pathogenesis and progression. Li M, Zhang Y, Liu Z, Bharadwaj U, Wang H, Wang X, Zhang S, Liuzzi JP, Chang SM, Cousins RJ, Fisher WE, Brunicardi FC, Logsdon CD, Chen C, Yao Q. Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18636-41. PMID: 18003899
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