|Application ||WB, E|
|Other Accession||NP_542763.1, 140809|
|Predicted||Mouse, Rat, Pig, Cow|
|Calculated MW||14259 Da|
|Other Names||Sulfiredoxin-1, 220.127.116.11, SRXN1, C20orf139, SRX|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SRX1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Contributes to oxidative stress resistance by reducing cysteine-sulfinic acid formed under exposure to oxidants in the peroxiredoxins PRDX1, PRDX2, PRDX3 and PRDX4. Does not act on PRDX5 or PRDX6. May catalyze the reduction in a multi-step process by acting both as a specific phosphotransferase and a thioltransferase.|
|Tissue Location||Widely expressed with highest levels in kidney, lung, spleen and thymus.|
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Provided below are standard protocols that you may find useful for product applications.
Structure of the sulphiredoxin-peroxiredoxin complex reveals an essential repair embrace. Jönsson TJ, Johnson LC, Lowther WT. Nature. 2008 Jan 3;451(7174):98-101. PMID: 18172504
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