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PSCA (aa27-40) Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O43653
Other Accession NP_005663.1, 8000
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 12912 Da
Additional Information
Other Names Prostate stem cell antigen, PSCA
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPSCA (aa27-40) Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function May be involved in the regulation of cell proliferation. Has a cell-proliferation inhibition activity in vitro.
Cellular Location Cell membrane; Lipid-anchor, GPI-anchor.
Tissue Location Highly expressed in prostate (basal, secretory and neuroendocrine epithelium cells). Also found in bladder (transitional epithelium), placenta (trophoblasts), stomach (neuroendocrine cells), colon (neuroendocrine cells) and kidney (collecting ducts). Overexpressed in prostate cancers and expression is correlated with tumor stage, grade and androgen- independence. Highly expressed in prostate cancer bone metastases Expressed in gastric epithelial cells, mainly in the isthmus (at protein level). Not detected in normal intestinal epithelium (at protein level).
Research Areas
Citations (0)

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Prostate stem cell antigen vaccination induces a long-term protective immune response against prostate cancer in the absence of autoimmunity. Garcia-Hernandez Mde L, Gray A, Hubby B, Klinger OJ, Kast WM. Cancer Res. 2008 Feb 1;68(3):861-9. PMID: 18245488

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$ 325.00
Cat# AF2861a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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