|Application ||IHC, E|
|Other Accession||NP_005950.1, 4544|
|Calculated MW||40188 Da|
|Other Names||Melatonin receptor type 1B, Mel-1B-R, Mel1b receptor, MTNR1B|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MTNR1B Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||High affinity receptor for melatonin. Likely to mediates the reproductive and circadian actions of melatonin. The activity of this receptor is mediated by pertussis toxin sensitive G proteins that inhibit adenylate cyclase activity.|
|Cellular Location||Cell membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in retina and less in brain and hippocampus|
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Provided below are standard protocols that you may find useful for product applications.
Melatonin suppresses nighttime memory formation in zebrafish. Rawashdeh O, de Borsetti NH, Roman G, Cahill GM. Science 2007 Nov 318 (5853): 1144-6. PMID: 18006748
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