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GABRB2 Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P47870
Other Accession NP_068711.1, NP_000804.1, 2561, 14401 (mouse), 25451 (rat)
Predicted Human, Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 59150 Da
Additional Information
Gene ID 2561
Other Names Gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2, GABRB2
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGABRB2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Function Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel.
Cellular Location Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein
Tissue Location Isoform 1 and isoform 2 show reduced expression in schizophrenic brain. Isoform 3 shows increased expression in schizophrenic and bipolar disorder brains while isoform 4 shows reduced expression.
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_068711.1; NP_000804.1).


Association of SNPs and haplotypes in GABAA receptor beta2 gene with schizophrenia. Lo WS, Lau CF, Xuan Z, Chan CF, Feng GY, He L, Cao ZC, Liu H, Luan QM, Xue H. Mol. Psychiatry 2004 Jun 9 (6): 603-8. PMID: 14699426

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$ 325.00
Cat# AF2887a
(40 western blots)
Availability: 7-10 days
Bulk Size
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