SULF2 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
---|---|
Primary Accession | Q8IWU5 |
Other Accession | NP_061325.1, NP_940998.1, 55959 |
Reactivity | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 100455 Da |
Gene ID | 55959 |
---|---|
Other Names | Extracellular sulfatase Sulf-2, hSulf-2, 3.1.6.-, SULF2, KIAA1247 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | SULF2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | SULF2 |
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Synonyms | KIAA1247 |
Function | Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity (PubMed:12368295, PubMed:30788513, PubMed:35294879). It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin (PubMed:12368295, PubMed:30788513, PubMed:35294879). |
Cellular Location | Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8VI60}. Golgi apparatus, Golgi stack {ECO:0000250|UniProtKB:Q8VI60}. Cell surface |
Tissue Location | Expressed at highest levels in the ovary, skeletal muscle, stomach, brain, uterus, heart, kidney and placenta |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize both reported isoforms (NP_061325.1; NP_940998.1)
References
HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo. Dai Y, Yang Y, MacLeod V, Yue X, Rapraeger AC, Shriver Z, Venkataraman G, Sasisekharan R, Sanderson RD. J Biol Chem. 2005 Dec 2;280(48):40066-73. PMID: 16192265
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