|Application ||WB, E|
|Other Accession||NP_061325.1, NP_940998.1, 55959|
|Calculated MW||100455 Da|
|Other Names||Extracellular sulfatase Sulf-2, hSulf-2, 3.1.6.-, SULF2, KIAA1247|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||SULF2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Exhibits arylsulfatase activity and highly specific endoglucosamine-6-sulfatase activity. It can remove sulfate from the C-6 position of glucosamine within specific subregions of intact heparin.|
|Cellular Location||Endoplasmic reticulum. Golgi apparatus, Golgi stack. Cell surface Note=Also localized on the cell surface.|
|Tissue Location||Expressed at highest levels in the ovary, skeletal muscle, stomach, brain, uterus, heart, kidney and placenta|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_061325.1; NP_940998.1)
HSulf-1 and HSulf-2 are potent inhibitors of myeloma tumor growth in vivo. Dai Y, Yang Y, MacLeod V, Yue X, Rapraeger AC, Shriver Z, Venkataraman G, Sasisekharan R, Sanderson RD. J Biol Chem. 2005 Dec 2;280(48):40066-73. PMID: 16192265
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