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HIP1R/ HIP12 Antibody (C-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75146
Other Accession NP_003950.1, 9026
Predicted Human, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 119388 Da
Additional Information
Gene ID 9026
Other Names Huntingtin-interacting protein 1-related protein, HIP1-related protein, Huntingtin-interacting protein 12, HIP-12, HIP1R, HIP12, KIAA0655
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsHIP1R/ HIP12 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name HIP1R
Synonyms HIP12, KIAA0655
Function Component of clathrin-coated pits and vesicles, that may link the endocytic machinery to the actin cytoskeleton. Binds 3- phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis.
Cellular Location Cytoplasm, perinuclear region. Endomembrane system. Cytoplasmic vesicle, clathrin-coated vesicle membrane Note=Membrane-associated protein, mainly localized at the endocytic compartments and in the perinuclear region
Tissue Location Brain, heart, kidney, pancreas, and liver, but not in lung or placenta
Research Areas
Citations (0)

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Clathrin light chains function in mannose phosphate receptor trafficking via regulation of actin assembly. Poupon V, Girard M, Legendre-Guillemin V, Thomas S, Bourbonniere L, Philie J, Bright NA, McPherson PS, Proc. Natl. Acad. Sci. U.S.A. 2008 Jan 105 (1): 168-73. PMID: 18165318

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$ 325.00
Cat# AF2912a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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