|Other Accession||NP_005742.4, NP_671714.1, 10142|
|Calculated MW||453667 Da|
|Other Names||A-kinase anchor protein 9, AKAP-9, A-kinase anchor protein 350 kDa, AKAP 350, hgAKAP 350, A-kinase anchor protein 450 kDa, AKAP 450, AKAP 120-like protein, Centrosome- and Golgi-localized PKN-associated protein, CG-NAP, Protein hyperion, Protein kinase A-anchoring protein 9, PRKA9, Protein yotiao, AKAP9, AKAP350, AKAP450, KIAA0803|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||AKAP9 / YOTIAO Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||AKAP350, AKAP450, KIAA0803|
|Function||Binds to type II regulatory subunits of protein kinase A. Scaffolding protein that assembles several protein kinases and phosphatases on the centrosome and Golgi apparatus. May be required to maintain the integrity of the Golgi apparatus. Isoform 4 is associated with the N-methyl-D-aspartate receptor and is specifically found in the neuromuscular junction (NMJ) as well as in neuronal synapses, suggesting a role in the organization of postsynaptic specializations.|
|Cellular Location||Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Golgi apparatus Note=Cytoplasmic in parietal cells|
|Tissue Location||Widely expressed. Isoform 4 is highly expressed in skeletal muscle and in pancreas|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoforms 2 and 3 (NP_005742.4; NP_671714.1)
Association of a common AKAP9 variant with breast cancer risk: a collaborative analysis. Frank B, Wiestler M, Kropp S, Hemminki K, Spurdle AB, Sutter C, Wappenschmidt B, Chen X, Beesley J, Hopper JL, Meindl A, Kiechle M, Slanger T, Bugert P, Schmutzler RK, Bartram CR, Flesch-Janys D, Mutschelknauss E, Ashton K, Salazar R, Webb E, Hamann U, Br J. Natl. Cancer Inst. 2008 Mar 100 (6): 437-42. PMID: 18334708
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