|Application ||WB, E|
|Other Accession||NP_006734.1, 5935, 19652 (mouse), 114488 (rat)|
|Predicted||Mouse, Rat, Dog|
|Calculated MW||17170 Da|
|Other Names||RNA-binding protein 3, RNA-binding motif protein 3, RNPL, RBM3, RNPL|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||RBM3 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Cold-inducible mRNA binding protein that enhances global protein synthesis at both physiological and mild hypothermic temperatures. Reduces the relative abundance of microRNAs, when overexpressed. Enhances phosphorylation of translation initiation factors and active polysome formation (By similarity).|
|Cellular Location||Nucleus. Cytoplasm. Cell projection, dendrite Note=Localizes in mRNA granules in dentrites.|
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Provided below are standard protocols that you may find useful for product applications.
Translation regulatory factor RBM3 is a proto-oncogene that prevents mitotic
catastrophe. Sureban SM, Ramalingam S, Natarajan G, May R, Subramaniam D, Bishnupuri KS, Morrison AR, Dieckgraefe BK, Brackett DJ, Postier RG, Houchen CW, Anant S. Oncogene. 2008 Jul 31;27(33):4544-56. PMID: 18427544
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