|Application ||IHC, E|
|Other Accession||NP_079488.1, 80319, 319478 (mouse)|
|Calculated MW||20978 Da|
|Other Names||CXXC-type zinc finger protein 4, Inhibition of the Dvl and axin complex protein, CXXC4, IDAX|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CXXC4 Antibody (C-Terminus, near) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Acts as a negative regulator of the Wnt signaling pathway via its interaction with DVL1.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Decreased expression of CXXC4 promotes a malignant phenotype in renal cell carcinoma by activating Wnt signaling. Kojima T, Shimazui T, Hinotsu S, Joraku A, Oikawa T, Kawai K, Horie R, Suzuki H, Nagashima R, Yoshikawa K, Michiue T, Asashima M, Akaza H, Uchida K. Oncogene 2008 Oct. [Epub ahead of print] PMID: 18931698
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