KCNQ3 Antibody (C-Term)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application ![]()
| E |
---|---|
Primary Accession | O43525 |
Other Accession | NP_004510.1, 3786, 110862 (mouse), 29682 (rat) |
Predicted | Human, Mouse, Rat, Pig |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 96742 Da |
Gene ID | 3786 |
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Other Names | Potassium voltage-gated channel subfamily KQT member 3, KQT-like 3, Potassium channel subunit alpha KvLQT3, Voltage-gated potassium channel subunit Kv7.3, KCNQ3 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | KCNQ3 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | KCNQ3 |
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Function | Probably important in the regulation of neuronal excitability. Associates with KCNQ2 or KCNQ5 to form a potassium channel with essentially identical properties to the channel underlying the native M-current, a slowly activating and deactivating potassium conductance which plays a critical role in determining the subthreshold electrical excitability of neurons as well as the responsiveness to synaptic inputs. |
Cellular Location | Membrane; Multi-pass membrane protein. |
Tissue Location | Predominantly expressed in brain. |

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Provided below are standard protocols that you may find useful for product applications.
References
Regulation of the voltage-gated K(+) channels KCNQ2/3 and KCNQ3/5 by ubiquitination. Novel role for Nedd4-2. Ekberg J, Schuetz F, Boase NA, Conroy SJ, Manning J, Kumar S, Poronnik P, Adams DJ. J Biol Chem. 2007 Apr 20;282(16):12135-42. PMID: 17322297

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