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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Goat Antibodies   >   ATG4D Antibody (internal region, near C-Term)   

ATG4D Antibody (internal region, near C-Term)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86TL0
Other Accession NP_116274.3, 84971, 235040 (mouse), 686505 (rat)
Predicted Human, Mouse, Rat, Pig, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 52922 Da
Additional Information
Gene ID 84971
Other Names Cysteine protease ATG4D, 3.4.22.-, AUT-like 4 cysteine endopeptidase, Autophagin-4, Autophagy-related cysteine endopeptidase 4, Autophagy-related protein 4 homolog D, Cysteine protease ATG4D, mitochondrial, ATG4D, APG4D, AUTL4
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsATG4D Antibody (internal region, near C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATG4D
Synonyms APG4D, AUTL4
Function Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Cellular Location Cysteine protease ATG4D: Cytoplasm.
Tissue Location Mainly expressed in skeletal muscle and, to a lower extent, in testis.
Research Areas
Citations (0)

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Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy. Mariño G, Uría JA, Puente XS, Quesada V, Bordallo J, López-Otín C. The Journal of biological chemistry 2003 Feb 278 (6): 3671-8. PMID: 12446702

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$ 325.00
Cat# AF2934a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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