|Application ||WB, IP, E|
|Other Accession||NP_065122.1, NP_001161049.1, NP_001161048.1, 57113, 26946 (mouse), 282822 (rat)|
|Predicted||Human, Mouse, Rat, Dog|
|Calculated MW||99562 Da|
|Other Names||Short transient receptor potential channel 7, TrpC7, Transient receptor protein 7, TRP-7, hTRP7, TRPC7, TRP7|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||TRPC7 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Nucleus envelope|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to cross-react with isoform 1, 2 and 3 (NP_065122.1; NP_001161049.1; NP_001161048.1).
TRPC3/6/7: Topical aspects of biophysics and pathophysiology. Eder P, Groschner K. Channels (Austin). 2008 Mar 29;2(2). [Epub ahead of print]. PMID: 18849655
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