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TRPC7 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, IP, E |
|---|---|
| Primary Accession | Q9HCX4 |
| Other Accession | NP_065122.1, NP_001161049.1, NP_001161048.1, 57113, 26946 (mouse), 282822 (rat) |
| Reactivity | Chicken |
| Predicted | Human, Mouse, Rat, Dog |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 99562 Da |
| Gene ID | 57113 |
|---|---|
| Other Names | Short transient receptor potential channel 7, TrpC7, Transient receptor protein 7, TRP-7, hTRP7, TRPC7, TRP7 |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | TRPC7 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | TRPC7 |
|---|---|
| Synonyms | TRP7 |
| Function | Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G- protein coupled receptors. Activated by diacylglycerol (DAG) (By similarity). May also be activated by intracellular calcium store depletion. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Nucleus envelope |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to cross-react with isoform 1, 2 and 3 (NP_065122.1; NP_001161049.1; NP_001161048.1).
References
TRPC3/6/7: Topical aspects of biophysics and pathophysiology. Eder P, Groschner K. Channels (Austin). 2008 Mar 29;2(2). [Epub ahead of print]. PMID: 18849655
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