|Other Accession||NP_005801.3, 10219|
|Calculated MW||21831 Da|
|Other Names||Killer cell lectin-like receptor subfamily G member 1, C-type lectin domain family 15 member A, ITIM-containing receptor MAFA-L, MAFA-like receptor, Mast cell function-associated antigen, KLRG1, CLEC15A, MAFA, MAFAL|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLRG1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CLEC15A, MAFA, MAFAL|
|Function||Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Frequent expression of the natural killer cell receptor KLRG1 in human cord blood T cells: correlation with replicative history. Marcolino I, Przybylski GK, Koschella M, Schmidt CA, Voehringer D, Schlesier M, Pircher H. European journal of immunology 2004 Oct 34 (10): 2672-80. PMID: 15368283
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