|Other Accession||NP_005801.3, 10219|
|Calculated MW||21831 Da|
|Other Names||Killer cell lectin-like receptor subfamily G member 1, C-type lectin domain family 15 member A, ITIM-containing receptor MAFA-L, MAFA-like receptor, Mast cell function-associated antigen, KLRG1, CLEC15A, MAFA, MAFAL|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||KLRG1 Antibody (N-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||CLEC15A, MAFA, MAFAL|
|Function||Plays an inhibitory role on natural killer (NK) cells and T-cell functions upon binding to their non-MHC ligands. May mediate missing self recognition by binding to a highly conserved site on classical cadherins, enabling it to monitor expression of E-cadherin/CDH1, N-cadherin/CDH2 and R-cadherin/CDH4 on target cells.|
|Cellular Location||Cell membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed specifically on natural killer (NK) cells and T-cells, mainly CD8 T-cells|
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Provided below are standard protocols that you may find useful for product applications.
Frequent expression of the natural killer cell receptor KLRG1 in human cord blood T cells: correlation with replicative history. Marcolino I, Przybylski GK, Koschella M, Schmidt CA, Voehringer D, Schlesier M, Pircher H. European journal of immunology 2004 Oct 34 (10): 2672-80. PMID: 15368283
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