|Other Accession||NP_003033.3, 6529, 79212 (rat)|
|Predicted||Human, Rat, Dog|
|Calculated MW||67074 Da|
|Other Names||Sodium- and chloride-dependent GABA transporter 1, GAT-1, Solute carrier family 6 member 1, SLC6A1, GABATR, GABT1, GAT1|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||GAT1 / SLC6A1 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||GABATR, GABT1, GAT1|
|Function||Terminates the action of GABA by its high affinity sodium-dependent reuptake into presynaptic terminals.|
|Cellular Location||Cell membrane; Multi-pass membrane protein. Membrane; Multi-pass membrane protein. Note=Localized at the plasma membrane and in a subset of intracellular vesicles Localized at the presynaptic terminals of interneurons (By similarity).|
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A common variant in DRD3 receptor is associated with autism spectrum disorder. de Krom M, Staal WG, Ophoff RA, Hendriks J, Buitelaar J, Franke B, de Jonge MV, Bolton P, Collier D, Curran S, van Engeland H, van Ree JM. Biol Psychiatry. 2009 Apr 1;65(7):625-30. PMID: 19058789
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