|Other Accession||NP_006757.2, 7994|
|Calculated MW||225028 Da|
|Other Names||Histone acetyltransferase KAT6A, 220.127.116.11, MOZ, YBF2/SAS3, SAS2 and TIP60 protein 3, MYST-3, Monocytic leukemia zinc finger protein, Runt-related transcription factor-binding protein 2, Zinc finger protein 220, KAT6A, MOZ, MYST3, RUNXBP2, ZNF220|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MOZ / KAT6A Antibody (Internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MOZ, MYST3, RUNXBP2, ZNF220|
|Function||Histone acetyltransferase that acetylates lysine residues in histone H3 and histone H4 (in vitro). Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. May act as a transcriptional coactivator for RUNX1 and RUNX2. Acetylates p53/TP53 at 'Lys-120' and 'Lys-382' and controls its transcriptional activity via association with PML.|
|Cellular Location||Nucleus. Nucleus, nucleolus. Nucleus, nucleoplasm. Nucleus, PML body. Note=Recruited into PML body after DNA damage|
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Provided below are standard protocols that you may find useful for product applications.
Reported variants NP_001092882.1, NP_006757.2, NP_001092883.1 represent identical protein.
Monocytic leukemia zinc finger (MOZ) interacts with p53 to induce p21 expression and cell-cycle arrest. Rokudai S, Aikawa Y, Tagata Y, Tsuchida N, Taya Y, Kitabayashi I. J Biol Chem. 2009 Jan 2;284(1):237-44. PMID: 19001415
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