WNT15 / WNT9B Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| WB, E |
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Primary Accession | O14905 |
Other Accession | NP_003387.1, 7484, 22412 (mouse), 303586 (rat) |
Reactivity | Human, Mouse |
Predicted | Rat |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 39001 Da |
Gene ID | 7484 |
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Other Names | Protein Wnt-9b, Protein Wnt-14b, Protein Wnt-15, WNT9B, WNT14B, WNT15 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | WNT15 / WNT9B Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | WNT9B |
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Synonyms | WNT14B {ECO:0000303|PubMed:11604992}, WN |
Function | Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt/beta-catenin signaling pathway. Required for normal embryonic kidney development, and for normal development of the urogenital tract, including uterus and part of the oviduct and the upper vagina in females, and epididymis and vas deferens in males. Activates a signaling cascade in the metanephric mesenchyme that induces tubulogenesis. Acts upstream of WNT4 in the signaling pathways that mediate development of kidney tubules and the Muellerian ducts. Plays a role in cranofacial development and is required for normal fusion of the palate during embryonic development (By similarity). |
Cellular Location | Secreted, extracellular space, extracellular matrix. Secreted |
Tissue Location | Moderately expressed in fetal kidney and adult kidney. Also found in brain |
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Provided below are standard protocols that you may find useful for product applications.
References
Variation in WNT genes is associated with non-syndromic cleft lip with or without cleft palate. Chiquet BT, Blanton SH, Burt A, Ma D, Stal S, Mulliken JB, Hecht JT. Hum Mol Genet. 2008 Jul 15;17(14):2212-8. Epub 2008 Apr 14. PMID: 18413325
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