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TMPRSS11D / HAT Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O60235
Other Accession NP_004253.1, 9407
Predicted Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 46263 Da
Additional Information
Gene ID 9407
Other Names Transmembrane protease serine 11D, 3.4.21.-, Airway trypsin-like protease, Transmembrane protease serine 11D non-catalytic chain, Transmembrane protease serine 11D catalytic chain, TMPRSS11D, HAT
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsTMPRSS11D / HAT Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms HAT
Function May play some biological role in the host defense system on the mucous membrane independently of or in cooperation with other substances in airway mucous or bronchial secretions. Plays a role in the proteolytic processing of ACE2. Proteolytically cleaves and activates the human coronavirus 229E (HCoV-229E) spike glycoprotein which facilitate virus-cell membrane fusions; spike proteins are synthesized and maintained in precursor intermediate folding states and proteolysis permits the refolding and energy release required to create stable virus-cell linkages and membrane coalescence.
Cellular Location Cell membrane; Single-pass type II membrane protein. Note=Activated by cleavage and secreted
Tissue Location Located in the cells of the submucosal serous glands of the bronchi and trachea
Research Areas
Citations (0)

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Proteolytic activation of influenza viruses by serine proteases TMPRSS2 and HAT from human airway epithelium. Böttcher E, Matrosovich T, Beyerle M, Klenk HD, Garten W, Matrosovich M. J Virol. 2006 Oct;80(19):9896-8. PMID: 16973594

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$ 325.00
Cat# AF2980a
(40 western blots)
Availability: 7-10 days
Bulk Size
Seasonal Special on Bulk Order
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