|Application ||WB, E|
|Other Accession||NP_003474.1, NP_003475.1, 8091|
|Calculated MW||11832 Da|
|Other Names||High mobility group protein HMGI-C, High mobility group AT-hook protein 2, HMGA2, HMGIC|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||HMGI-C / HMGA2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Functions as a transcriptional regulator. Functions in cell cycle regulation through CCNA2. Plays an important role in chromosome condensation during the meiotic G2/M transition of spermatocytes.|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_003474.1; NP_003475.1) and is not expected to cross-react with HMGA1.
Expression and cDNA cloning of human HMGI-C phosphoprotein Patel UA, Bandiera A, Manfioletti G, Giancotti V, Chau KY, Crane-Robinson C Biochem Biophys Res Commun. 1994 May 30;201(1):63-70. PMID: 8198613
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