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ATXN1 Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P54253
Other Accession NP_000323.2, 6310
Predicted Human, Pig, Dog
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 86923 Da
Additional Information
Gene ID 6310
Other Names Ataxin-1, Spinocerebellar ataxia type 1 protein, ATXN1, ATX1, SCA1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsATXN1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ATXN1
Synonyms ATX1, SCA1
Function Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.
Cellular Location Cytoplasm. Nucleus. Note=Colocalizes with USP7 in the nucleus
Tissue Location Widely expressed throughout the body.
Research Areas
Citations (0)

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Reported variant NP_000323.2 and NP_001121636.1 represent identical protein.


Identification and characterization of the gene causing type 1 spinocerebellar ataxia Banfi S, Servadio A, Chung MY, Kwiatkowski TJ Jr, McCall AE, Duvick LA, Shen Y, Roth EJ, Orr HT, Zoghbi HY Nat. Genet. 1994 Aug 7 (4): 513-20 PMID: 7951322

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$ 325.00
Cat# AF3019a
(40 western blots)
Availability: 7-10 days
Bulk Size
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