|Other Accession||NP_004878.2, 9547, 57266 (mouse), 306748 (rat)|
|Predicted||Human, Mouse, Rat, Dog, Cow|
|Calculated MW||13078 Da|
|Other Names||C-X-C motif chemokine 14, Chemokine BRAK, MIP-2G, Small-inducible cytokine B14, CXCL14, MIP2G, NJAC, SCYB14|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CXCL14 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||MIP2G, NJAC, SCYB14|
|Function||Potent chemoattractant for neutrophils, and weaker for dendritic cells. Not chemotactic for T-cells, B-cells, monocytes, natural killer cells or granulocytes. Does not inhibit proliferation of myeloid progenitors in colony formation assays.|
|Tissue Location||Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Highly expressed in normal tissue without inflammatory stimuli and infrequently expressed in cancer cell lines. Weakly expressed in monocyte- derived dendritic cells. Not detected in lung or unstimulated peripheral blood lymphocytes.|
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Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. Siezen CL, Bont L, Hodemaekers HM, Ermers MJ, Doornbos G, Van't Slot R, Wijmenga C, Houwelingen HC, Kimpen JL, Kimman TG, Hoebee B, Janssen R. The Pediatric infectious disease journal 2009 Apr 28 (4): 333-5. PMID: 19258923
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