|Application ||IHC, E|
|Other Accession||NP_004582.1, NP_001123518.1, 6364|
|Calculated MW||10762 Da|
|Other Names||C-C motif chemokine 20, Beta-chemokine exodus-1, CC chemokine LARC, Liver and activation-regulated chemokine, Macrophage inflammatory protein 3 alpha, MIP-3-alpha, Small-inducible cytokine A20, CCL20(1-67), CCL20(1-64), CCL20(2-70), CCL20, LARC, MIP3A, SCYA20|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||CCL20 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Synonyms||LARC, MIP3A, SCYA20|
|Function||Chemotactic factor that attracts lymphocytes and, slightly, neutrophils, but not monocytes. Inhibits proliferation of myeloid progenitors in colony formation assays. May be involved in formation and function of the mucosal lymphoid tissues by attracting lymphocytes and dendritic cells towards epithelial cells. C-terminal processed forms have been shown to be equally chemotactically active for leukocytes. Possesses antibacterial activity E.coli ATCC 25922 and S.aureus ATCC 29213.|
|Tissue Location||Expressed predominantly in the liver, lymph nodes, appendix, peripheral blood lymphocytes, and fetal lung. Low levels seen in thymus, prostate, testis, small intestine and colon|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both isoforms (NP_004582.1; NP_001123518.1).
Induction of CCL20 production by Kaposi sarcoma-associated herpesvirus: role of viral FLICE inhibitory protein K13-induced NF-kappaB activation. Punj V, Matta H, Schamus S, Yang T, Chang Y, Chaudhary PM, Blood 2009 May 113 (22): 5660-8. PMID: 19324905
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