|Other Accession||NP_056234.2, 25878|
|Calculated MW||312150 Da|
|Other Names||Matrix-remodeling-associated protein 5, Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan, Adlican, MXRA5|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||MXRA5 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||In kidney, has anti-inflammatory and anti-fibrotic properties by limiting the induction of chemokines, fibronectin and collagen expression in response to TGB1 and pro-inflammatory stimuli.|
|Tissue Location||Highly expressed in kidney, also detected on liver and spleen (PubMed:27599751). Expressed by proximal tubular cells of the kidney (at protein level) (PubMed:27599751) Expression highly increases during chronic kidney disease and autosomal dominant polycystic kidney disease, where is detected in cysts (PubMed:27599751).|
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Provided below are standard protocols that you may find useful for product applications.
Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. Fu GK, Wang JT, Yang J, Au-Young J, Stuve LL. Genomics 2004 Jul 84 (1): 205-10. PMID: 15203218
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