MXRA5 Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application
| E |
---|---|
Primary Accession | Q9NR99 |
Other Accession | NP_056234.2, 25878 |
Predicted | Human |
Host | Goat |
Clonality | Polyclonal |
Concentration | 0.5 mg/ml |
Isotype | IgG |
Calculated MW | 312150 Da |
Gene ID | 25878 |
---|---|
Other Names | Matrix-remodeling-associated protein 5, Adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan, Adlican, MXRA5 |
Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
Precautions | MXRA5 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
Name | MXRA5 |
---|---|
Function | In kidney, has anti-inflammatory and anti-fibrotic properties by limiting the induction of chemokines, fibronectin and collagen expression in response to TGB1 and pro-inflammatory stimuli. |
Cellular Location | Secreted |
Tissue Location | Detected in placenta (at protein level) (PubMed:32337544). Detected in cerebrospinal fluid and fibroblasts (at protein level) (PubMed:25326458, PubMed:36213313). Highly expressed in kidney, also detected on liver and spleen (PubMed:27599751). Expressed by proximal tubular cells of the kidney (at protein level) (PubMed:27599751). Expression highly increases during chronic kidney disease and autosomal dominant polycystic kidney disease, where is detected in cysts (PubMed:27599751). |
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Provided below are standard protocols that you may find useful for product applications.
References
Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes. Fu GK, Wang JT, Yang J, Au-Young J, Stuve LL. Genomics 2004 Jul 84 (1): 205-10. PMID: 15203218
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