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GPR17 Antibody (C-Term)

Peptide-affinity purified goat antibody

     
  • WB - GPR17 Antibody (C-Term) AF3047a
    AF3047a (0.1 µg/ml) staining of Human Cerebellum lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
    detail
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession Q13304
Other Accession NP_005282.1, 2840, 574402 (mouse), 767613 (rat)
Reactivity Human, Mouse, Rat
Predicted Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 40989 Da
Additional Information
Gene ID 2840
Other Names Uracil nucleotide/cysteinyl leukotriene receptor, UDP/CysLT receptor, G-protein coupled receptor 17, P2Y-like receptor, R12, GPR17
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsGPR17 Antibody (C-Term) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPR17
Function Dual specificity receptor for uracil nucleotides and cysteinyl leukotrienes (CysLTs). Signals through G(i) and inhibition of adenylyl cyclase. May mediate brain damage by nucleotides and CysLTs following ischemia.
Cellular Location Cell membrane; Multi-pass membrane protein.
Tissue Location Expressed in brain, kidney, heart and umbilical vein endothelial cells. Highest level in brain
Research Areas
Citations (0)
citation

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References

GPR17: molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2Y receptors. Parravicini C, Ranghino G, Abbracchio MP, Fantucci P, BMC bioinformatics 2008 9 : 263. PMID: 18533035

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$ 341.00
Cat# AF3047a
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Availability: 7-10 days
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