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PRPF6 Antibody (Internal region)

Peptide-affinity purified goat antibody

     
  • WB - PRPF6 Antibody (Internal region) AF3048a
    AF3048a (1 µg/ml) staining of Jurkat nuclear lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession O94906
Other Accession NP_036601.2, 24148, 68879 (mouse), 366276 (rat)
Reactivity Human
Predicted Mouse, Rat, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 106925 Da
Additional Information
Gene ID 24148
Other Names Pre-mRNA-processing factor 6, Androgen receptor N-terminal domain-transactivating protein 1, ANT-1, PRP6 homolog, U5 snRNP-associated 102 kDa protein, U5-102 kDa protein, PRPF6, C20orf14
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRPF6 Antibody (Internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRPF6
Synonyms C20orf14
Function Involved in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex, one of the building blocks of the spliceosome (PubMed:28781166, PubMed:21549338). Enhances dihydrotestosterone- induced transactivation activity of AR, as well as dexamethasone- induced transactivation activity of NR3C1, but does not affect estrogen-induced transactivation.
Cellular Location Nucleus, nucleoplasm. Nucleus speckle. Note=Localized in splicing speckles.
Tissue Location Widely expressed..
Research Areas
Citations (0)
citation

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References

The expression and bioinformatic analysis of a novel gene C20orf14 associated with lymphoma. Su L, Chen D, Zhang J, Li X, Pan G, Bai X, Lu Y, Zhou J, Li S, Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban 2008 Feb 28 (1): 97-101. PMID: 18278469

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$ 341.00
Cat# AF3048a
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Availability: 7-10 days
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