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DTX2 / Deltext-2 Antibody (internal region)

Peptide-affinity purified goat antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q86UW9
Other Accession NP_065943.2, NP_001096066.1, 113878, 304591 (rat)
Predicted Human, Rat, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 67246 Da
Additional Information
Gene ID 113878
Other Names Probable E3 ubiquitin-protein ligase DTX2, 6.3.2.-, Protein deltex-2, Deltex2, hDTX2, RING finger protein 58, DTX2, KIAA1528, RNF58
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsDTX2 / Deltext-2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name DTX2
Synonyms KIAA1528, RNF58
Function Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Probably acts both as a positive and negative regulator of Notch, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Functions as a ubiquitin ligase protein in vitro, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity.
Cellular Location Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Partially nuclear
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_065943.2; NP_001096066.1). Reported variants NP_001096065.1, NP_065943.2, NP_001096064.1 represent identical protein.


cDNA cloning, characterization and expression analysis of DTX2, a human WWE and RING-finger gene, in human embryos. Yi Z, Yi T, Wu Z, DNA sequence : the journal of DNA sequencing and mapping 2006 Jun 17 (3): 175-80. PMID: 17286044

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$ 325.00
Cat# AF3052a
(40 western blots)
Availability: 7-10 days
Bulk Size
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