|Other Accession||NP_060243.2, NP_001129662.1, 54900|
|Calculated MW||44085 Da|
|Other Names||Lymphocyte transmembrane adapter 1, Linker for activation of X cells, Membrane-associated adapter protein LAX, LAX1, LAX|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||LAX1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Negatively regulates TCR (T-cell antigen receptor)- mediated signaling in T-cells and BCR (B-cell antigen receptor)- mediated signaling in B-cells.|
|Cellular Location||Cell membrane; Single-pass type III membrane protein|
|Tissue Location||Expressed in spleen, thymus, and peripheral blood leukocytes. Expressed in several B-, T-, NK and monocyte cell lines.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize both reported isoforms (NP_060243.2; NP_001129662.1).
Molecular cloning of a novel gene encoding a membrane-associated adaptor protein (LAX) in lymphocyte signaling. Zhu M, Janssen E, Leung K, Zhang W, The Journal of biological chemistry 2002 Nov 277 (48): 46151-8. PMID: 12359715
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.