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PRDM1 / MEL1 Antibody (internal region)

Peptide-affinity purified goat antibody

  • WB - PRDM1 / MEL1 Antibody (internal region) AF3056a
    AF3056a (0.3 µg/ml) staining of A431 lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
  • IHC - PRDM1 / MEL1 Antibody (internal region) AF3056a
    AF3056a (3.8 µg/ml) staining of paraffin embedded Human Tonsil. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O75626
Other Accession NP_001189.2, NP_878911.1, 639, 12142 (mouse), 309871 (rat)
Reactivity Human
Predicted Mouse, Rat, Pig, Dog, Cow
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 91771 Da
Additional Information
Gene ID 639
Other Names PR domain zinc finger protein 1, 2.1.1.-, BLIMP-1, Beta-interferon gene positive regulatory domain I-binding factor, PR domain-containing protein 1, Positive regulatory domain I-binding factor 1, PRDI-BF1, PRDI-binding factor 1, PRDM1, BLIMP1
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsPRDM1 / MEL1 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name PRDM1
Synonyms BLIMP1
Function Transcriptional repressor that binds specifically to the PRDI element in the promoter of the beta-interferon gene (PubMed:1851123). Drives the maturation of B-lymphocytes into Ig secreting cells (PubMed:12626569).
Cellular Location Nucleus {ECO:0000250|UniProtKB:Q60636}. Cytoplasm
Research Areas
Citations (0)

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This antibody is expected to recognize both reported isoforms (NP_001189.2; NP_878911.1).


RelB NF-kappaB represses estrogen receptor alpha expression via induction of the zinc finger protein Blimp1. Wang X, Belguise K, O'Neill CF, Sánchez-Morgan N, Romagnoli M, Eddy SF, Mineva ND, Yu Z, Min C, Trinkaus-Randall V, Chalbos D, Sonenshein GE. Molecular and cellular biology 2009 Jul 29 (14): 3832-44. PMID: 19433448

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$ 325.00
Cat# AF3056a
(40 western blots)
Availability: 7-10 days
Bulk Size
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