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PCDH11Y / PCDH11X Antibody (internal region)
Peptide-affinity purified goat antibody
- SPECIFICATION
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Application 
| IHC, Pep-ELISA |
|---|---|
| Primary Accession | Q9BZA8 |
| Other Accession | NP_116753.1, NP_116754.1, NP_116755.1, NP_055337.1, NP_055337.1, NP_116750.1, NP_116751.1, 83259, 27328 |
| Predicted | Human |
| Host | Goat |
| Clonality | Polyclonal |
| Concentration | 0.5 mg/ml |
| Isotype | IgG |
| Calculated MW | 146775 Da |
| Gene ID | 83259 |
|---|---|
| Other Names | Protocadherin-11 Y-linked, Protocadherin-11, Protocadherin on the Y chromosome, PCDH-Y, Protocadherin prostate cancer, Protocadherin-PC, Protocadherin-22, PCDH11Y, PCDH11, PCDH22, PCDHY |
| Format | 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | PCDH11Y / PCDH11X Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | PCDH11Y |
|---|---|
| Synonyms | PCDH11, PCDH22, PCDHY |
| Function | Potential calcium-dependent cell-adhesion protein. |
| Cellular Location | Cell membrane; Single-pass type I membrane protein |
| Tissue Location | Expressed strongly in fetal brain and brain (cortex, amygdala, thalamus, substantia nigra, hippocampus, caudate nucleus and corpus callosum). Expressed at low level in testis Expressed in apoptosis-resistant cells. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This antibody is expected to recognize all reported Y-linked isoforms (NP_116753.1; NP_116754.1; NP_116755.1) and all reported X-linked isoforms (NP_055337.1; NP_055337.1; NP_116750.1; NP_116751.1).
References
Evidence for positive selection on Protocadherin Y gene in Homo sapiens: implications for schizophrenia. Kalmady SV, Venkatasubramanian G, Schizophrenia research 2009 Mar 108 (1-3): 299-300. PMID: 18938061
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