|Application ||WB, IHC, E|
|Other Accession||NP_004075.1, NP_005208.1, 1667, 1668|
|Calculated MW||10245 Da|
|Other Names||Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP-3, HP3, HP 3-56, Neutrophil defensin 2, HNP-2, HP-2, HP2, DEFA3, DEF3|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||DEFA1/3 precursor Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Defensin 2 and defensin 3 have antibiotic, fungicide and antiviral activities. Has antimicrobial activity against Gram- negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to equally recognize DEFA1 precursor and DEFA3 precursor.
Dual role of alpha-defensin-1 in anti-HIV-1 innate immunity. Chang TL, Vargas J Jr, DelPortillo A, Klotman ME. J Clin Invest. 2005 Mar;115(3):765-73. PMID: 15719067
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