|Other Accession||NP_001119600.1, 60675|
|Calculated MW||14314 Da|
|Other Names||Prokineticin-2, PK2, Protein Bv8 homolog, PROK2, BV8|
|Format||0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.|
|Precautions||Prokineticin 2 Antibody (internal region) is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||May function as an output molecule from the suprachiasmatic nucleus (SCN) that transmits behavioral circadian rhythm. May also function locally within the SCN to synchronize output. Potently contracts gastrointestinal (GI) smooth muscle.|
|Tissue Location||Expressed in the testis and, at low levels, in the small intestine|
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Provided below are standard protocols that you may find useful for product applications.
This antibody is expected to recognize isoform a (NP_001119600.1).
Loss-of-function mutation in the prokineticin 2 gene causes Kallmann syndrome and normosmic idiopathic hypogonadotropic hypogonadism. Pitteloud N, Zhang C, Pignatelli D, Li JD, Raivio T, Cole LW, Plummer L, Jacobson-Dickman EE, Mellon PL, Zhou QY, Crowley WF, Proc. Natl. Acad. Sci. U.S.A. 2007 Oct 104 (44): 17447-52. PMID: 17959774
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