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ANAPC11 Antibody (Internal region)

Peptide-affinity purified goat antibody

  • WB - ANAPC11 Antibody (Internal region) AF3076a
    AF3076a (1 µg/ml) staining of Cerebral Cortex lysate (35 µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9NYG5
Other Accession NP_001002244.1, NP_057560.8, 51529
Reactivity Human
Host Goat
Clonality Polyclonal
Concentration 0.5 mg/ml
Isotype IgG
Calculated MW 9841 Da
Additional Information
Gene ID 51529
Other Names Anaphase-promoting complex subunit 11, APC11, Cyclosome subunit 11, Hepatocellular carcinoma-associated RING finger protein, ANAPC11
Format 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
PrecautionsANAPC11 Antibody (Internal region) is for research use only and not for use in diagnostic or therapeutic procedures.
Protein Information
Name ANAPC11
Function Together with the cullin protein ANAPC2, constitutes the catalytic component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. May recruit the E2 ubiquitin-conjugating enzymes to the complex.
Cellular Location Cytoplasm. Nucleus
Tissue Location Expressed at high levels in skeletal muscle and heart; in moderate levels in brain, kidney, and liver; and at low levels in colon, thymus, spleen, small intestine, placenta, lung and peripheral blood leukocyte
Research Areas
Citations (0)

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This antibody is expected to recognize. Reported variants represent identical protein: NP_057560.8, NP_001002248.1, NP_001002245.1, NP_001002246.1, NP_001002247.1, NP_001002249.1


The RING-H2-finger protein APC11 as a target of hydrogen peroxide. Chang TS, Jeong W, Lee DY, Cho CS, Rhee SG, Free radical biology & medicine 2004 Aug 37 (4): 521-30. PMID: 15256223

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$ 325.00
Cat# AF3076a
(40 western blots)
Availability: 7-10 days
Bulk Size
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